1.掌管;〔俚语〕(事物)控制不住,弄糟
1.to take over control or responsibility for somebody or something
2.to take control and become responsible for someone or something
1.The boss asked me to take charge of the company when he was on holiday.
老板去度假的时候要我来负责公司。
2.He turned away; there was no sadness in him, no remorse. It was time to leave this shack and take charge.
他转过身子，没有悲伤，没有悔疚。是时候离开这棚屋，去掌握全局了。
3.The boss asked him to take charge of the office for a few days while she was away.
老板让他在她离开时掌管办公室几天。
4.Haiti's government is in no position to take charge, yet the country needs a strong government to put it to rights.
海地政府并未准备好负起责任，然而这个国家需要一个强势的政府来使一切恢复正常。
5.Since it has happened, let me take charge of recovering everything! Our company should not be passive any longer!
那么已经这样了，让我来负责把所有事情复原吧！咱们公司不能太被动了！
6.Senior officials described nervousness within the administration about how quickly Afghanistan will be ready to take charge.
政府高级官员面露紧张地描述了不久将来阿富汗被接管的情形。
7.When we have begun to take charge of our lives, to own ourselves, there is no longer any need to ask permission of someone.
当我们开始复责自己的生活，做自己的主人，就再也没有必要请求别人的允许了。
8.Ed Miliband seems at least to be taking this seriously, having appointed Liz Kendall to the shadow cabinet to take charge of social care.
毕竟我们还有米利班德，他似乎正在认真考虑这个问题，米利班德任命利兹.肯德尔为影子内阁成员，让他负责社会关怀事务。
9.Another MDC source added: "Gono has tried to take the money but Biti is trying to take charge. "
另一MDC来源补充道：“戈诺试图拿走资金，但是比提尽力看管这批资金。”
10.While you could feel a pinch, this only prompts you to take charge of your practical affairs.
你觉得手头很紧，但这会促使你对手边的实际事务负责。